Narcoleptic Patients' Perceptions of Nicotine

Elevated Peripheral Visfatin Levels in Narcoleptic Patients

OBJECTIVE Narcolepsy is a severe sleep disorder that is characterized by excessive daytime sleepiness, cataplexies and a tendency towards obesity. Recent discoveries indicate that the major pathophysiology is a loss of hypocretin (orexin) producing neurons due to immunologically mediated degeneration. Visfatin is a recently described proinflammatory adipokine. It is identical to the immune modu...

Eating disorder and metabolism in narcoleptic patients.

STUDY OBJECTIVE To evaluate eating behavior and energy balance as a cause of increased body mass index (BMI) in narcolepsy. DESIGN Case controlled pilot study. SETTINGS University hospital. PARTICIPANTS 13 patients with narcolepsy (7 "typical" patients, with HLA DQB1*0602 and clear cut cataplexy, with suspected hypocretin deficiency; and 6 "atypical" narcoleptics, i.e., HLA negative or wi...

Sustained attention assessment of narcoleptic patients: two case reports

Narcolepsy is a sleep disorder characterized by uncontrollable REM sleep attacks which alter the patients wake state and can lead to difficulties in attention aspects, such as maintaining attention when performing activities or tasks. This study aimed to evaluate sustained attention performance of two narcoleptic patients on the d2 Test, Epworth Sleepiness Scale (ESS), Pittsburgh Sleep Quality ...

Is High IQ Protective Against Cognitive Dysfunction in Narcoleptic Patients?

BACKGROUND AND PURPOSE The aims of this study were to elucidate the cognitive functions of narcoleptics and determine whether intelligence protects against cognitive dysfunction and depressive mood in these patients. METHODS Sixty-six subjects (33 narcoleptics, 33 controls) were administered a battery of neuropsychological tests and an individual standardized intelligence test. The cognitive ...

The narcoleptic borderland.